KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BARD1
All Species:
16.36
Human Site:
S274
Identified Species:
36
UniProt:
Q99728
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99728
NP_000456.2
777
86648
S274
T
E
S
E
C
F
G
S
L
T
E
V
S
L
P
Chimpanzee
Pan troglodytes
XP_526019
777
86498
S274
T
E
S
E
C
F
G
S
L
T
E
V
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001084740
777
86841
S274
T
E
S
E
C
F
G
S
L
T
E
V
S
L
P
Dog
Lupus familis
XP_852715
923
103188
S420
T
E
S
Q
C
F
S
S
L
A
E
V
S
L
P
Cat
Felis silvestris
Mouse
Mus musculus
O70445
765
84236
P262
A
S
G
S
V
V
E
P
E
C
S
G
S
L
T
Rat
Rattus norvegicus
Q9QZH2
768
84530
S264
A
S
G
S
V
V
E
S
V
F
S
G
S
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519813
231
26178
Chicken
Gallus gallus
NP_001026417
750
82934
S261
S
S
Q
E
E
D
N
S
K
A
V
C
P
V
Q
Frog
Xenopus laevis
NP_001082131
772
86896
I264
K
N
D
T
P
E
E
I
S
P
N
W
N
K
C
Zebra Danio
Brachydanio rerio
XP_001921099
334
36093
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188296
940
102732
S314
D
S
E
K
K
S
H
S
K
T
K
S
V
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.3
68.3
N.A.
69.5
68.5
N.A.
22.5
51.6
47.3
22.1
N.A.
N.A.
N.A.
N.A.
26.8
Protein Similarity:
100
99.7
97.5
74.4
N.A.
81
80.9
N.A.
26.7
67.9
62.8
31.6
N.A.
N.A.
N.A.
N.A.
41.4
P-Site Identity:
100
100
100
80
N.A.
13.3
13.3
N.A.
0
13.3
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
13.3
20
N.A.
0
26.6
6.6
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% A
% Cys:
0
0
0
0
37
0
0
0
0
10
0
10
0
0
10
% C
% Asp:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
37
10
37
10
10
28
0
10
0
37
0
0
0
0
% E
% Phe:
0
0
0
0
0
37
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
19
0
0
0
28
0
0
0
0
19
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
10
0
0
0
19
0
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
37
0
0
0
0
46
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
10
0
0
10
0
10
0
0
10
0
37
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
37
37
19
0
10
10
64
10
0
19
10
55
0
0
% S
% Thr:
37
0
0
10
0
0
0
0
0
37
0
0
0
10
10
% T
% Val:
0
0
0
0
19
19
0
0
10
0
10
37
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _